Mird237 Today

: Researchers have found that levels of MIRD237 can fluctuate significantly in patients with various types of tumors. Depending on the specific cancer, it may act as an "oncomiR" (promoting tumor growth) or a "tumor suppressor" (inhibiting it).

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This was revolutionary. A beta-emitting radionuclide bound to a monoclonal antibody might never enter the cell nucleus, but if it sits on the cell membrane, the nucleus receives a significant cross-fire dose. MIRD237 provided the numerical tables to calculate this precisely. mird237