Malignant | Deaufosse

Diagnosis requires full-thickness excisional biopsy with narrow margins for histopathologic evaluation. Key histologic features: atypical melanocytes, pagetoid spread, mitotic figures, and depth measured as Breslow thickness. Immunohistochemistry (S100, HMB-45, Melan-A) aids diagnosis. Staging follows the AJCC system integrating Breslow depth, ulceration, and nodal/distant metastasis.

If left untreated or if treatment is delayed, Malignant Deafness can lead to serious complications, including: malignant deaufosse

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